When Xander was very young someone laid a blessing or a curse, depending on your point of view, on Xander.  The blessing was that if someone pissed off Xander then bas things would happen to that person.  Now enought very bad would happen to that person but they would have a string of bad luck. 

For example if you were a bad guy then the good guy would always defeat you.  Or if a guy would develop an embarrassing case of jock itch right before his big date with a cheerleader.  For a girl should could break the heel on her new heels or a demon with a camera is around when the knot on your handkerchief shirt fails.

So what would happen if Xander went on a road trip and meet new and interesting people and got pissed off.

~*~

What would happen to character like Nick or Warrick if Xander got pissed off on Greg's behalf (CSI Las Vegas)

Or if he say how the members of Team Gibbs treated Tony (NCIS)